TNFSF15

Across TCGA patient cohorts, TNFSF15 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF15-associated genes across cancer lineages are MEP, Class-switched memory B-cells, and Adipocytes. Each is linked with TNFSF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF15-to-partner and partner-to-TNFSF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by TNFSF15-low versus TNFSF15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF15→partner) and Y-score (partner→TNFSF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEP →	+0.061	+2.891	<.001	.031	3	2
SKCM	Class-switched memory B-cells →	-0.040	-2.268	.025	.025	3	1
COAD	Adipocytes →	+0.041	+2.431	.007	.048	3	1
UCEC	aDC →	+0.090	+3.010	.035	.020	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MEP by TNFSF15 expression — UCEC

Explore this box plot interactively →