TNFSF15

Across TCGA cell cohorts, TNFSF15 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,385 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNFSF15-associated GO terms across cancer lineages are Establishment of endothelial intestinal barrier, Response to steroid hormone, and Small GTPase-mediated signal transduction. Each is linked with TNFSF15 in more than 11 cancer types. Because this analysis shows association rather than direction, both TNFSF15-to-partner and partner-to-TNFSF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of endothelial intestinal barrier grouped by TNFSF15-low versus TNFSF15-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF15→partner) and Y-score (partner→TNFSF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Establishment of endothelial intestinal barrier →	+0.190	+1.483	<.001	<.001	3	11
OVARY	Response to steroid hormone →	+0.089	+0.959	<.001	<.001	2	12
OVARY	Small GTPase-mediated signal transduction →	+0.050	+1.176	<.001	.002	3	9
OVARY	Rho protein signal transduction →	+0.102	+1.236	<.001	<.001	3	9
STOMACH	Negative regulation of actin filament polymerization →	+0.121	+1.392	.002	.009	2	10
OVARY	Positive regulation of sodium ion transmembrane transport →	+0.250	+0.904	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,385 associations by consensus.

Establishment of endothelial intestinal barrier by TNFSF15 expression — OESOPHAGUS

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