TNFSF15

Across TCGA cell cohorts, TNFSF15 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNFSF15-associated genes across cancer lineages are ZBBX and SALL3. Each is linked with TNFSF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF15-to-partner and partner-to-TNFSF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZBBX grouped by TNFSF15-low versus TNFSF15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF15→partner) and Y-score (partner→TNFSF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZBBX →	+0.133	+3.777	<.001	.007	3	1
LARGE_INTESTINE	SALL3 →	+0.087	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ZBBX by TNFSF15 expression — LARGE_INTESTINE

Explore this box plot interactively →