TNFSF14

Across TCGA cell cohorts, TNFSF14 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,275 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TNFSF14-associated GO terms across cancer lineages are Complement-mediated synapse pruning, Vertebrate eye-specific patterning, and Opsonization. Each is linked with TNFSF14 in more than 16 cancer types. Because this analysis shows association rather than direction, both TNFSF14-to-partner and partner-to-TNFSF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Complement-mediated synapse pruning grouped by TNFSF14-low versus TNFSF14-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF14→partner) and Y-score (partner→TNFSF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Complement-mediated synapse pruning →	+1.923	+0.256	<.001	<.001	3	17
SOFT_TISSUE	Vertebrate eye-specific patterning →	+1.897	+0.259	<.001	<.001	3	17
SOFT_TISSUE	Opsonization →	+2.036	+0.262	<.001	<.001	3	15
SOFT_TISSUE	Positive regulation of complement activation →	+2.044	+0.259	<.001	<.001	3	14
URINARY_TRACT	Complement activation, GZMK pathway →	+1.690	+0.473	<.001	.001	3	14
URINARY_TRACT	Positive regulation of apoptotic cell clearance →	+1.257	+0.451	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,275 associations by consensus.

Complement-mediated synapse pruning by TNFSF14 expression — SOFT_TISSUE

Explore this box plot interactively →