TNFSF14

Across TCGA cell cohorts, TNFSF14 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNFSF14-associated genes across cancer lineages are USP29, WFDC6, and C6orf118. Each is linked with TNFSF14 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF14-to-partner and partner-to-TNFSF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP29 grouped by TNFSF14-low versus TNFSF14-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF14→partner) and Y-score (partner→TNFSF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	USP29 →	+0.006	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	WFDC6 →	+0.036	+4.887	.002	.009	3	1
LARGE_INTESTINE	C6orf118 →	+0.130	+3.793	<.001	.007	3	1
LARGE_INTESTINE	COX6A2 →	+0.082	+4.437	<.001	.004	3	1
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

USP29 by TNFSF14 expression — OESOPHAGUS

Explore this box plot interactively →