TNFSF13

Across TCGA patient cohorts, TNFSF13 mutation is significantly associated with the RNA expression of many other genes, with 329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF13-associated genes across cancer lineages are RNU7-110P, RPL23AP90, and CCDC34P1. Each is linked with TNFSF13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF13-to-partner and partner-to-TNFSF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-110P grouped by TNFSF13-low versus TNFSF13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF13→partner) and Y-score (partner→TNFSF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU7-110P →	+0.525	+2.801	.001	.002	3	2
UCEC	RPL23AP90 →	+0.450	+3.159	<.001	<.001	3	1
SKCM	CCDC34P1 →	+0.145	+6.199	<.001	.001	3	1
SKCM	ATP5F1EP1 →	+0.277	+5.097	<.001	.008	3	1
SKCM	CACNA1C-IT1 →	+0.056	+5.097	.001	.008	3	1
BRCA	MIR4287 →	+0.431	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 329 associations by consensus.

RNU7-110P by TNFSF13 expression — UCEC

Explore this box plot interactively →