TNFSF12

Across TCGA patient cohorts, TNFSF12 protein abundance is significantly associated with the protein abundance of many other proteins, with 5,170 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TNFSF12-associated proteins across cancer lineages are TLR7, RBSN_S236, and TNS1_S364. Each is linked with TNFSF12 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFSF12-to-partner and partner-to-TNFSF12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF12 versus TLR7 in GBM, with a Pearson correlation of 0.80.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF12→partner) and Y-score (partner→TNFSF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLR7 →	+0.734	+0.391	.005	<.001	3	3
LUAD	RBSN_S236 →	+1.164	+0.986	<.001	<.001	3	2
UCEC	TNS1_S364 →	+1.076	+0.823	.001	.001	3	2
LUAD	UBE4B_S803 →	-1.341	-0.861	.002	.003	3	2
LUAD	ZFAND3_S129 →	-1.377	-0.870	.001	<.001	3	2
LUAD	HAMP →	+0.693	+0.606	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,170 associations by consensus.

TNFSF12 vs TLR7 — GBM

Explore this scatter interactively →