TNFSF12

Across TCGA cell cohorts, TNFSF12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,692 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TNFSF12-associated GO terms across cancer lineages are Muscle organ development, Negative regulation of G1/S transition of mitotic cell cycle, and Positive regulation of supramolecular fiber organization. Each is linked with TNFSF12 in more than 10 cancer types. Because this analysis shows association rather than direction, both TNFSF12-to-partner and partner-to-TNFSF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Muscle organ development grouped by TNFSF12-low versus TNFSF12-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF12→partner) and Y-score (partner→TNFSF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Muscle organ development →	+0.121	+2.065	.002	.003	3	10
BONE	Negative regulation of G1/S transition of mitotic cell cycle →	+0.094	+2.305	.001	<.001	3	10
BONE	Positive regulation of supramolecular fiber organization →	+0.088	+2.208	.001	.001	2	11
BONE	Positive regulation of plasma membrane repair →	+0.335	+2.318	<.001	<.001	3	10
LUNG_NSCLC_LUSC	PML body organization →	+0.235	+2.382	.008	.002	3	9
BONE	Membrane fusion involved in viral entry into host cell →	+0.252	+1.692	.003	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,692 associations by consensus.

Muscle organ development by TNFSF12 expression — BONE

Explore this box plot interactively →