TNFSF11

Across TCGA patient cohorts, TNFSF11 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,768 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFSF11-associated proteins across cancer lineages are P3H3, OLFML2B, and CALD1. Each is linked with TNFSF11 in more than 5 cancer types. Because this analysis shows association rather than direction, both TNFSF11-to-partner and partner-to-TNFSF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF11 versus P3H3 in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF11→partner) and Y-score (partner→TNFSF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	P3H3 →	+0.570	+0.778	<.001	<.001	3	6
GBM	OLFML2B →	+0.700	+0.401	<.001	<.001	3	5
LSCC	CALD1 →	+0.845	+0.716	<.001	<.001	3	5
GBM	CNN2 →	+0.622	+0.272	<.001	<.001	3	5
GBM	COL5A1 →	+0.861	+0.328	<.001	<.001	3	5
LSCC	FILIP1L →	+0.652	+0.732	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,768 associations by consensus.

TNFSF11 vs P3H3 — BRCA

Explore this scatter interactively →