TNFSF11

Across TCGA cell cohorts, TNFSF11 protein abundance is significantly associated with the RNA expression of many other genes, with 2,174 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNFSF11-associated genes across cancer lineages are DMAC2L, TOGARAM1, and GJB3. Each is linked with TNFSF11 in more than 7 cancer types. Because this analysis shows association rather than direction, both TNFSF11-to-partner and partner-to-TNFSF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFSF11 versus DMAC2L in OESOPHAGUS, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF11→partner) and Y-score (partner→TNFSF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DMAC2L →	+0.812	+0.904	.004	.003	3	8
STOMACH	TOGARAM1 →	+1.330	+1.325	<.001	.001	3	6
LUNG_NSCLC_LUAD	GJB3 →	+2.301	+0.705	<.001	.008	3	5
BLOOD_Lymphoma	SSR2 →	-1.078	-0.820	.002	.005	3	5
BREAST	SNRNP40 →	-0.685	-1.076	.001	.001	3	5
LARGE_INTESTINE	C4orf46 →	-0.687	-0.927	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,174 associations by consensus.

TNFSF11 vs DMAC2L — OESOPHAGUS

Explore this scatter interactively →