TNFRSF6B

Across TCGA patient cohorts, TNFRSF6B RNA expression is significantly associated with the go_rna of many other GO terms, with 422 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible TNFRSF6B-associated GO terms across cancer lineages are Response to acid chemical, Transcription elongation-coupled chromatin remodeling, and Bicarbonate transport. Each is linked with TNFRSF6B in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF6B-to-partner and partner-to-TNFRSF6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to acid chemical grouped by TNFRSF6B-low versus TNFRSF6B-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF6B→partner) and Y-score (partner→TNFRSF6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Response to acid chemical →	+0.069	+0.894	<.001	<.001	3	1
SCLC	Transcription elongation-coupled chromatin remodeling →	+0.146	+1.146	<.001	<.001	3	1
SCLC	Bicarbonate transport →	-0.084	-1.483	<.001	<.001	3	1
SCLC	Autophagosome membrane docking →	+0.077	+1.038	<.001	<.001	3	1
SCLC	Cytosolic transport →	+0.079	+1.114	<.001	<.001	3	1
SCLC	Obsolete histone modification →	+0.067	+0.960	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 422 associations by consensus.

Response to acid chemical by TNFRSF6B expression — SCLC

Explore this box plot interactively →