TNFRSF6B

Across TCGA cell cohorts, TNFRSF6B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,639 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TNFRSF6B-associated GO terms across cancer lineages are Negative regulation of t-circle formation, Actomyosin contractile ring assembly actin filament organization, and Calcium-independent cell-matrix adhesion. Each is linked with TNFRSF6B in more than 9 cancer types. Because this analysis shows association rather than direction, both TNFRSF6B-to-partner and partner-to-TNFRSF6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of t-circle formation grouped by TNFRSF6B-low versus TNFRSF6B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF6B→partner) and Y-score (partner→TNFRSF6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of t-circle formation →	+0.142	+3.669	<.001	.001	3	10
SOFT_TISSUE	Actomyosin contractile ring assembly actin filament organization →	+0.233	+1.737	<.001	<.001	3	9
BONE	Calcium-independent cell-matrix adhesion →	+0.150	+0.776	.007	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of autophagy →	+0.068	+2.750	.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular protein transport →	+0.077	+2.442	<.001	.004	3	8
URINARY_TRACT	Negative regulation of small GTPase mediated signal transduction →	+0.066	+2.362	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,639 associations by consensus.

Negative regulation of t-circle formation by TNFRSF6B expression — PANCREAS

Explore this box plot interactively →