TNFRSF4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TNFRSF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,216 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TNFRSF4-associated GO terms across cancer lineages are tRNA transcription by RNA polymerase III, Excitatory postsynaptic potential, and Microtubule bundle formation. Each is linked with TNFRSF4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TNFRSF4-to-partner and partner-to-TNFRSF4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF4→partner) and Y-score (partner→TNFRSF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTtRNA transcription by RNA polymerase III →+0.075+0.083.007.00534
URINARY_TRACTExcitatory postsynaptic potential →-0.082-0.057.002.00834
BLOOD_LymphomaMicrotubule bundle formation →-0.034-2.187<.001.00234
BLOOD_LymphomaPositive regulation of membrane repolarization during ventricular cardiac muscle cell action potential →+0.895+2.038<.001<.00134
BLOOD_LymphomaPositive regulation of membrane repolarization during cardiac muscle cell action potential →+0.895+2.038<.001<.00134
BLOOD_LymphomaCellular response to thyroid hormone stimulus →+0.107+1.736<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,216 associations by consensus.

Exploration