Across TCGA patient cohorts, TNFRSF25 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,734 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFRSF25-associated proteins across cancer lineages are PLEKHG5_S959, RCC2, and PRPF4B_S294. Each is linked with TNFRSF25 in more than 3 cancer types. Because this analysis shows association rather than direction, both TNFRSF25-to-partner and partner-to-TNFRSF25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF25→partner) and Y-score (partner→TNFRSF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEKHG5_S959 →	+0.628	+0.830	.001	.005	3	4
LSCC	RCC2 →	+0.341	+0.516	<.001	<.001	3	4
PDAC	PRPF4B_S294 →	+0.855	+0.633	<.001	<.001	3	3
BRCA	CDC123 →	+0.400	+0.812	.002	.001	3	3
LUAD	AGR2 →	-0.880	-0.509	<.001	<.001	3	3
LSCC	HDLBP →	-0.228	-0.545	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,734 associations by consensus.

Exploration

TNFRSF25 survival (RNA) · tumor vs normal (RNA) · all TNFRSF25 data types