TNFRSF25

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFRSF25 mutation is significantly associated with the RNA expression of many other genes, with 1,726 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFRSF25-associated genes across cancer lineages are CENPVL1, HIRIP3, and NOCT. Each is linked with TNFRSF25 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF25-to-partner and partner-to-TNFRSF25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF25→partner) and Y-score (partner→TNFRSF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCENPVL1 →+0.024+7.954<.001.00832
UCECHIRIP3 →+0.385+2.747.009<.00132
UCECNOCT →+0.589+3.914<.001<.00132
UCECSKA1 →+0.743+2.747<.001<.00132
UCECLEO1 →+0.399+3.732.007<.00132
UCECFEN1 →+0.580+3.087.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,726 associations by consensus.

Exploration