TNFRSF1B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFRSF1B protein abundance is significantly associated with the RNA expression of many other genes, with 13,247 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFRSF1B-associated genes across cancer lineages are TMEM201, LCNL1, and NELFCD. Each is linked with TNFRSF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF1B-to-partner and partner-to-TNFRSF1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF1B versus TMEM201 in LSCC, with a Pearson correlation of -0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF1B→partner) and Y-score (partner→TNFRSF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTMEM201 →-0.537-0.367.002.00932
LSCCLCNL1 →+0.241+0.334.001.00632
LSCCNELFCD →-0.714-0.486<.001<.00132
LSCCTIMP1 →+0.668+0.495.001.00232
LSCCNUFIP2 →-0.486-0.427<.001<.00132
LSCCC17orf75 →-0.575-0.341<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,247 associations by consensus.

TNFRSF1B vs TMEM201 — LSCC

Per-sample scatter of TNFRSF1B vs TMEM201 in LSCC (Pearson r = -0.25).

Explore this scatter interactively →

Exploration