TNFRSF1B

Across TCGA patient cohorts, TNFRSF1B mutation is significantly associated with the RNA expression of many other genes, with 717 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFRSF1B-associated genes across cancer lineages are RNU6-1261P, RN7SL835P, and MTCO1P46. Each is linked with TNFRSF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF1B-to-partner and partner-to-TNFRSF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1261P grouped by TNFRSF1B-low versus TNFRSF1B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF1B→partner) and Y-score (partner→TNFRSF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1261P →	+0.301	+4.859	<.001	.004	3	2
BLCA	RN7SL835P →	+0.253	+3.959	.003	.006	3	2
SKCM	MTCO1P46 →	+0.030	+3.141	.005	.006	3	2
COAD	RNU6-709P →	+0.742	+6.142	<.001	<.001	3	2
BLCA	RN7SL51P →	+0.389	+6.329	<.001	<.001	3	2
CESC	GAPDHP56 →	+0.028	+5.569	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 717 associations by consensus.

RNU6-1261P by TNFRSF1B expression — BLCA

Explore this box plot interactively →