TNFRSF1B

Across TCGA cell cohorts, TNFRSF1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,834 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNFRSF1B-associated GO terms across cancer lineages are Glial cell-neuron signaling, Antigen processing and presentation of exogenous peptide antigen via MHC class Ib, and Negative regulation of proteolysis. Each is linked with TNFRSF1B in more than 12 cancer types. Because this analysis shows association rather than direction, both TNFRSF1B-to-partner and partner-to-TNFRSF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glial cell-neuron signaling grouped by TNFRSF1B-low versus TNFRSF1B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF1B→partner) and Y-score (partner→TNFRSF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Glial cell-neuron signaling →	-0.240	-1.397	<.001	<.001	3	13
BREAST	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.308	+1.172	<.001	<.001	3	10
BONE	Negative regulation of proteolysis →	+0.146	+1.123	<.001	<.001	3	9
BONE	Barbed-end actin filament capping →	+0.218	+1.098	<.001	<.001	3	9
BONE	Negative regulation of epithelial cell apoptotic process →	+0.150	+1.048	<.001	<.001	3	9
BREAST	Negative regulation of immune response →	+0.091	+0.949	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,834 associations by consensus.

Glial cell-neuron signaling by TNFRSF1B expression — SOFT_TISSUE

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