TNFRSF19

Across TCGA patient cohorts, TNFRSF19 mutation is significantly associated with the RNA expression of many other genes, with 1,543 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFRSF19-associated genes across cancer lineages are RN7SL478P, UHRF1, and CALHM6. Each is linked with TNFRSF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF19-to-partner and partner-to-TNFRSF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL478P grouped by TNFRSF19-low versus TNFRSF19-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF19→partner) and Y-score (partner→TNFRSF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL478P →	+0.216	+5.219	<.001	.006	3	2
UCEC	UHRF1 →	+0.642	+1.595	.003	.006	3	2
UCEC	CALHM6 →	+0.761	+2.584	.002	.001	3	2
UCEC	ZNF79 →	+0.371	+1.874	<.001	.002	3	2
UCEC	FICD →	+0.406	+1.914	.001	.009	3	2
UCEC	RNU6-597P →	+0.339	+1.785	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,543 associations by consensus.

RN7SL478P by TNFRSF19 expression — READ

Explore this box plot interactively →