Across TCGA patient cohorts, TNFRSF18 protein abundance is significantly associated with the RNA expression of many other genes, with 1,866 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TNFRSF18-associated genes across cancer lineages are PPFIBP2, CEBPB, and LINC02595. Each is linked with TNFRSF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF18-to-partner and partner-to-TNFRSF18 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF18→partner) and Y-score (partner→TNFRSF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPFIBP2 →	-0.818	-1.061	.004	<.001	3	2
UCEC	CEBPB →	+1.077	+1.503	<.001	<.001	3	2
LUAD	LINC02595 →	+2.030	+1.215	<.001	<.001	3	2
LUAD	KIF15 →	+1.373	+0.937	<.001	.005	3	2
HNSC	WDR72 →	+1.204	+0.797	.008	.001	3	2
HNSC	RPS3AP23 →	+1.212	+0.843	.005	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,866 associations by consensus.

Exploration

TNFRSF18 survival (RNA) · tumor vs normal (RNA) · all TNFRSF18 data types