Across TCGA cell cohorts, TNFRSF18 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,819 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TNFRSF18-associated GO terms across cancer lineages are Regulation of myoblast fusion, Protein targeting to ER, and Extracellular vesicle biogenesis. Each is linked with TNFRSF18 in more than 6 cancer types. Because this analysis shows association rather than direction, both TNFRSF18-to-partner and partner-to-TNFRSF18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF18→partner) and Y-score (partner→TNFRSF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.081	+1.917	<.001	.001	3	7
OESOPHAGUS	Protein targeting to ER →	+0.090	+2.230	.004	.002	3	7
LUNG_NSCLC_LUAD	Extracellular vesicle biogenesis →	+0.120	+1.498	.004	.004	3	7
CNS	Protein stabilization →	+0.033	+0.319	.002	.002	3	7
BLOOD_Lymphoma	Microtubule bundle formation →	-0.035	-2.549	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Spliceosomal conformational changes to generate catalytic conformation →	+0.042	+1.114	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,819 associations by consensus.

Exploration

TNFRSF18 survival (RNA) · tumor vs normal (RNA) · all TNFRSF18 data types