TNFRSF17

Across TCGA patient cohorts, TNFRSF17 mutation is significantly associated with the RNA expression of many other genes, with 1,643 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFRSF17-associated genes across cancer lineages are RNA5SP222, C1orf50, and MVD. Each is linked with TNFRSF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF17-to-partner and partner-to-TNFRSF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP222 grouped by TNFRSF17-low versus TNFRSF17-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF17→partner) and Y-score (partner→TNFRSF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP222 →	+0.286	+7.731	<.001	.009	3	2
UCEC	C1orf50 →	+0.313	+2.265	.006	.006	3	2
UCEC	MVD →	+0.658	+3.370	<.001	.004	3	2
UCEC	THOP1 →	+0.588	+3.467	<.001	.002	3	2
UCEC	TIPIN →	+0.535	+2.928	.001	.001	3	2
UCEC	WDR62 →	+0.740	+3.480	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,643 associations by consensus.

RNA5SP222 by TNFRSF17 expression — BRCA

Explore this box plot interactively →