TNFRSF13B

Across TCGA patient cohorts, TNFRSF13B mutation is significantly associated with the RNA expression of many other genes, with 943 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFRSF13B-associated genes across cancer lineages are OR5M1, ZBTB8OS, and ORC6. Each is linked with TNFRSF13B in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF13B-to-partner and partner-to-TNFRSF13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5M1 grouped by TNFRSF13B-low versus TNFRSF13B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF13B→partner) and Y-score (partner→TNFRSF13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR5M1 →	+0.041	+5.569	<.001	.002	3	2
UCEC	ZBTB8OS →	+0.392	+2.254	.001	.006	3	2
UCEC	ORC6 →	+0.637	+2.606	.003	.005	3	2
UCEC	RNU6-222P →	+0.446	+2.349	<.001	.003	3	2
SKCM	MIR215 →	+0.366	+2.521	<.001	<.001	3	2
SKCM	MIR1231 →	+0.097	+4.528	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 943 associations by consensus.

OR5M1 by TNFRSF13B expression — CESC

Explore this box plot interactively →