TNFRSF13B

Across TCGA patient cohorts, TNFRSF13B mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFRSF13B-associated genes across cancer lineages are Caspase-7-cleavedD198, FASN, and EGFR_pY1068. Each is linked with TNFRSF13B in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFRSF13B-to-partner and partner-to-TNFRSF13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by TNFRSF13B-low versus TNFRSF13B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF13B→partner) and Y-score (partner→TNFRSF13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.660	+2.341	.010	.019	3	3
UCEC	FASN →	+0.375	+2.115	.029	.019	3	2
UCEC	EGFR_pY1068 →	-0.237	-2.807	.030	.003	3	1
UCEC	EGFR →	-0.201	-2.115	.004	.019	3	1
UCEC	Notch1 →	+0.148	+2.179	.016	.034	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.404	-2.321	.039	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Caspase-7-cleavedD198 by TNFRSF13B expression — UCEC

Explore this box plot interactively →