TNFRSF11B

Across TCGA patient cohorts, TNFRSF11B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,705 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFRSF11B-associated proteins across cancer lineages are COL8A1, HSPB7, and CNN1. Each is linked with TNFRSF11B in more than 3 cancer types. Because this analysis shows association rather than direction, both TNFRSF11B-to-partner and partner-to-TNFRSF11B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF11B versus COL8A1 in GBM, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF11B→partner) and Y-score (partner→TNFRSF11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	COL8A1 →	+1.029	+1.142	<.001	<.001	3	4
BRCA	HSPB7 →	+0.684	+1.492	<.001	<.001	3	4
BRCA	CNN1 →	+0.706	+0.925	<.001	.007	3	3
BRCA	EFEMP1 →	+0.735	+1.028	<.001	.002	3	3
BRCA	FGF2 →	+0.606	+1.072	<.001	<.001	3	3
LSCC	FLNA_S11 →	+0.806	+1.009	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,705 associations by consensus.

TNFRSF11B vs COL8A1 — GBM

Explore this scatter interactively →