TNFRSF11B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFRSF11B protein abundance is significantly associated with the RNA expression of many other genes, with 2,483 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFRSF11B-associated genes across cancer lineages are CARD10, MPST, and MSI1. Each is linked with TNFRSF11B in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF11B-to-partner and partner-to-TNFRSF11B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF11B versus CARD10 in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF11B→partner) and Y-score (partner→TNFRSF11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCARD10 →-0.780-1.084<.001<.00132
OVMPST →-0.795-1.177<.001<.00132
OVMSI1 →-1.335-0.942<.001.00532
LSCCZNF74 →-0.655-0.802<.001.00832
LSCCFRRS1L →-0.813-0.847<.001<.00132
UCECTMEM176A →+1.148+0.650.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,483 associations by consensus.

TNFRSF11B vs CARD10 — OV

Per-sample scatter of TNFRSF11B vs CARD10 in OV (Pearson r = -0.34).

Explore this scatter interactively →

Exploration