TNFRSF11B

Across TCGA cell cohorts, TNFRSF11B RNA expression is significantly associated with the RNA expression of many other genes, with 8,151 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TNFRSF11B-associated genes across cancer lineages are NNMT, FBN1, and ARSJ. Each is linked with TNFRSF11B in more than 6 cancer types. Because this analysis shows association rather than direction, both TNFRSF11B-to-partner and partner-to-TNFRSF11B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF11B versus NNMT in BONE, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF11B→partner) and Y-score (partner→TNFRSF11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	NNMT →	+4.850	+3.351	<.001	<.001	3	7
BONE	FBN1 →	+4.794	+4.029	<.001	<.001	3	6
SOFT_TISSUE	ARSJ →	+2.150	+2.454	<.001	<.001	3	6
BONE	DLGAP4 →	+1.166	+4.475	<.001	<.001	3	6
CNS	TNS3 →	+2.724	+2.731	<.001	<.001	3	6
CNS	APOL1 →	+2.936	+3.624	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,151 associations by consensus.

TNFRSF11B vs NNMT — BONE

Explore this scatter interactively →