TNFRSF11B

Across TCGA cell cohorts, TNFRSF11B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,346 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TNFRSF11B-associated GO terms across cancer lineages are Protein targeting to membrane, Cellular response to chemical stress, and Viral process. Each is linked with TNFRSF11B in more than 9 cancer types. Because this analysis shows association rather than direction, both TNFRSF11B-to-partner and partner-to-TNFRSF11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to membrane grouped by TNFRSF11B-low versus TNFRSF11B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF11B→partner) and Y-score (partner→TNFRSF11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein targeting to membrane →	+0.074	+4.162	<.001	<.001	3	10
SOFT_TISSUE	Cellular response to chemical stress →	+0.048	+2.278	<.001	<.001	3	9
BONE	Viral process →	+0.101	+3.884	<.001	<.001	3	9
SOFT_TISSUE	Negative regulation of sensory perception of pain →	+1.390	+3.285	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Negative regulation of epithelial cell apoptotic process →	+0.214	+2.501	.003	.009	3	8
BONE	Negative regulation of type B pancreatic cell apoptotic process →	+0.184	+3.752	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,346 associations by consensus.

Protein targeting to membrane by TNFRSF11B expression — BONE

Explore this box plot interactively →