TNFAIP8L3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFAIP8L3 mutation is significantly associated with the RNA expression of many other genes, with 271 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFAIP8L3-associated genes across cancer lineages are CDY3P, RNU6-744P, and SLC6A14P2. Each is linked with TNFAIP8L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L3-to-partner and partner-to-TNFAIP8L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L3→partner) and Y-score (partner→TNFAIP8L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READCDY3P →+0.050+7.276<.001<.00133
BLCARNU6-744P →+0.691+6.484<.001<.00132
COADSLC6A14P2 →+0.153+7.741<.001.00932
LUSCLINC01595 →+0.400+5.093<.001.00832
UCECRNU6-441P →+0.197+4.470<.001.00432
UCECUBDP1 →+0.073+4.245<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 271 associations by consensus.

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