Across TCGA patient cohorts, TNFAIP8L3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFAIP8L3-associated genes across cancer lineages are Neurons, Pericytes, and Sebocytes. Each is linked with TNFAIP8L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L3-to-partner and partner-to-TNFAIP8L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L3→partner) and Y-score (partner→TNFAIP8L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Neurons →	+0.016	+1.341	.024	.045	3	1
UCEC	Pericytes →	+0.041	+2.113	.005	.024	3	1
UCEC	Sebocytes →	-0.032	-2.916	.017	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

TNFAIP8L3 survival (RNA) · tumor vs normal (RNA) · all TNFAIP8L3 data types