Across TCGA cell cohorts, TNFAIP8L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,602 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TNFAIP8L3-associated GO terms across cancer lineages are 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process, Neuropilin signaling pathway, and Positive regulation of focal adhesion assembly. Each is linked with TNFAIP8L3 in more than 7 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L3-to-partner and partner-to-TNFAIP8L3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L3→partner) and Y-score (partner→TNFAIP8L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process →	-0.097	-0.519	<.001	.004	3	8
BONE	Neuropilin signaling pathway →	+0.201	+2.016	.008	<.001	3	8
BONE	Positive regulation of focal adhesion assembly →	+0.163	+1.460	<.001	<.001	3	8
SKIN	Regulation of gene silencing by regulatory ncRNA →	+0.059	+0.422	<.001	<.001	3	8
BONE	Regulation of plasminogen activation →	+0.222	+1.459	<.001	<.001	3	8
BONE	Regulation of apoptotic signaling pathway →	+0.061	+1.565	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,602 associations by consensus.

Exploration

TNFAIP8L3 survival (RNA) · tumor vs normal (RNA) · all TNFAIP8L3 data types