Across TCGA pan-cancer cohorts, TNFAIP8L1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TNFAIP8L1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TNFAIP8L1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TNFAIP8L1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LUAD, UCEC, and LSCC are the cancer types where TNFAIP8L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.338	1.000	.005	41	view →
UCEC	OS	Quartile	All	0.568	1.000	.004	16	view →
LSCC	OS	Median	III,IV	0.843	0.440	.021	7	view →
HNSC	DFS	Tertile	III,IV	0.403	1.000	.016	4	view →
CCRCC	OS	Median	All	0.929	0.574	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: TNFAIP8L1 tumor-vs-normal RNA expression · all TNFAIP8L1 data types