Across TCGA patient cohorts, TNFAIP8L1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,474 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TNFAIP8L1-associated genes across cancer lineages are RHOJ, ESAM, and CDH5. Each is linked with TNFAIP8L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFAIP8L1-to-partner and partner-to-TNFAIP8L1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8L1→partner) and Y-score (partner→TNFAIP8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RHOJ →	+0.850	+0.420	<.001	<.001	3	3
CCRCC	ESAM →	+0.980	+0.337	<.001	<.001	3	3
CCRCC	CDH5 →	+0.869	+0.373	<.001	<.001	3	3
UCEC	ARHGEF15 →	+0.789	+0.395	.001	.001	3	3
UCEC	PCAT19 →	+1.290	+0.450	<.001	<.001	3	3
LUAD	CCDC6 →	-0.603	-0.491	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,474 associations by consensus.

Exploration

TNFAIP8L1 survival (RNA) · tumor vs normal (RNA) · all TNFAIP8L1 data types