TNFAIP8

Across TCGA patient cohorts, TNFAIP8 protein abundance is significantly associated with the RNA expression of many other genes, with 20,463 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TNFAIP8-associated genes across cancer lineages are PLEK, CD48, and TNFSF14. Each is linked with TNFAIP8 in more than 9 cancer types. Because this analysis shows association rather than direction, both TNFAIP8-to-partner and partner-to-TNFAIP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFAIP8 versus PLEK in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8→partner) and Y-score (partner→TNFAIP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEK →	+1.312	+0.970	<.001	<.001	3	10
HNSC	CD48 →	+0.997	+0.392	<.001	<.001	3	10
CCRCC	TNFSF14 →	+1.088	+0.359	<.001	<.001	3	10
HNSC	CD53 →	+1.571	+0.638	<.001	<.001	3	10
COAD	GBP5 →	+1.681	+0.577	<.001	<.001	3	10
HNSC	CCR5 →	+1.157	+0.477	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,463 associations by consensus.

TNFAIP8 vs PLEK — GBM

Explore this scatter interactively →