TNFAIP8

Across TCGA cell cohorts, TNFAIP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,085 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TNFAIP8-associated GO terms across cancer lineages are Negative regulation of T cell mediated immunity, Regulation of actin filament depolymerization, and Plasma membrane organization. Each is linked with TNFAIP8 in more than 9 cancer types. Because this analysis shows association rather than direction, both TNFAIP8-to-partner and partner-to-TNFAIP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of T cell mediated immunity grouped by TNFAIP8-low versus TNFAIP8-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP8→partner) and Y-score (partner→TNFAIP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of T cell mediated immunity →	+0.134	+0.789	.002	.006	2	10
BONE	Regulation of actin filament depolymerization →	+0.115	+0.851	.007	.005	3	8
BREAST	Plasma membrane organization →	+0.080	+1.183	.002	<.001	3	7
LIVER	Wound healing →	+0.087	+1.245	.001	.001	3	7
KIDNEY	Tissue remodeling →	+0.102	+1.488	<.001	.001	3	7
OVARY	Regulation of monocyte aggregation →	+1.033	+1.351	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,085 associations by consensus.

Negative regulation of T cell mediated immunity by TNFAIP8 expression — PANCREAS

Explore this box plot interactively →