Across TCGA patient cohorts, TNFAIP2 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFAIP2-associated genes across cancer lineages are EGFR_pY1068, Caspase-7-cleavedD198, and Ku80. Each is linked with TNFAIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFAIP2-to-partner and partner-to-TNFAIP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFAIP2→partner) and Y-score (partner→TNFAIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.252	-2.906	.018	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.535	+1.700	.033	.044	3	2
UCEC	Ku80 →	+0.368	+2.710	<.001	.003	3	1
UCEC	MAPK_pT202_Y204 →	-0.427	-2.000	.032	.030	3	1
UCEC	Akt →	+0.211	+3.335	.029	.005	3	1
UCEC	Annexin-1 →	+0.720	+3.584	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

TNFAIP2 survival (RNA) · tumor vs normal (RNA) · all TNFAIP2 data types