TNFAIP1

Across TCGA pan-cancer cohorts, TNFAIP1 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TNFAIP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TNFAIP1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types TNFAIP1 is over-expressed in tumor, although a few such as LUAD and PDAC show the opposite, repressed pattern.

LUAD, PDAC, and LSCC are the cancer types where TNFAIP1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TNFAIP1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.367	<.001	6	view →
PDAC	Male	All	−0.457	.002	4	view →
LSCC	All	All	−0.256	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

TNFAIP1–LUAD

Open the LUAD breakdown →