TMX3

Across TCGA patient cohorts, TMX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,762 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TMX3-associated proteins across cancer lineages are SMAD4, VPS4B, and SMAD2. Each is linked with TMX3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMX3-to-partner and partner-to-TMX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMX3 versus SMAD4 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMX3→partner) and Y-score (partner→TMX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SMAD4 →	+0.308	+0.825	.001	<.001	3	7
COAD	VPS4B →	+0.208	+0.501	<.001	<.001	3	6
COAD	SMAD2 →	+0.476	+0.498	<.001	<.001	3	5
LUAD	CTDP1 →	+0.185	+0.394	<.001	<.001	3	5
OV	NARS1 →	+0.330	+0.609	.001	.002	3	5
GBM	MBD1 →	+0.351	+0.500	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,762 associations by consensus.

TMX3 vs SMAD4 — OV

Explore this scatter interactively →