TMX3

Across TCGA cell cohorts, TMX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,389 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMX3-associated GO terms across cancer lineages are Centrosome cycle, Microtubule organizing center organization, and DNA damage tolerance. Each is linked with TMX3 in more than 13 cancer types. Because this analysis shows association rather than direction, both TMX3-to-partner and partner-to-TMX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by TMX3-low versus TMX3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMX3→partner) and Y-score (partner→TMX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Centrosome cycle →	+0.084	+0.953	.001	<.001	3	14
OESOPHAGUS	Microtubule organizing center organization →	+0.081	+0.989	.001	<.001	3	13
LUNG_SCLC	DNA damage tolerance →	+0.096	+0.886	<.001	<.001	3	13
BREAST	Regulation of maintenance of sister chromatid cohesion →	+0.095	+1.033	<.001	<.001	3	13
BREAST	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.095	+1.033	<.001	<.001	3	13
LUNG_SCLC	Translesion synthesis →	+0.075	+0.608	.005	.004	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,389 associations by consensus.

Centrosome cycle by TMX3 expression — OESOPHAGUS

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