TMX3

Across TCGA cell cohorts, TMX3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMX3-associated genes across cancer lineages are TAFA1, NKX2-6, and TLE7. Each is linked with TMX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMX3-to-partner and partner-to-TMX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAFA1 grouped by TMX3-low versus TMX3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMX3→partner) and Y-score (partner→TMX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAFA1 →	+0.274	+3.688	<.001	.002	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TAFA1 by TMX3 expression — LARGE_INTESTINE

Explore this box plot interactively →