Across TCGA patient cohorts, TMX2 mutation is significantly associated with the RNA expression of many other genes, with 1,688 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMX2-associated genes across cancer lineages are RNY3P11, CCDC134, and CAMTA2. Each is linked with TMX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMX2-to-partner and partner-to-TMX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMX2→partner) and Y-score (partner→TMX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNY3P11 →	+0.560	+5.306	<.001	.006	3	2
UCEC	CCDC134 →	+0.499	+2.269	.001	.001	3	2
UCEC	CAMTA2 →	+0.389	+2.617	.001	.005	3	2
UCEC	PANX2 →	+0.908	+2.247	.002	.002	3	2
SKCM	OPALIN →	+0.019	+2.855	<.001	.009	3	2
UCEC	RNU6-4P →	+0.455	+1.971	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,688 associations by consensus.

Exploration

TMX2 survival (RNA) · tumor vs normal (RNA) · all TMX2 data types