TMTC3

Across TCGA patient cohorts, TMTC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,262 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMTC3-associated proteins across cancer lineages are CYSLTR1_S326, MANBAL, and ST6GAL1. Each is linked with TMTC3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMTC3-to-partner and partner-to-TMTC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMTC3 versus CYSLTR1_S326 in LUAD, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMTC3→partner) and Y-score (partner→TMTC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CYSLTR1_S326 →	-1.057	-0.530	<.001	<.001	3	6
BRCA	MANBAL →	+0.672	+0.605	<.001	.001	2	6
LSCC	ST6GAL1 →	-0.809	-0.815	<.001	<.001	3	5
BRCA	FRMD6_S544 →	+1.013	+0.718	<.001	<.001	3	5
GBM	SCYL2 →	+0.188	+0.363	.007	.001	3	5
UCEC	PTPRC →	-0.650	-0.412	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,262 associations by consensus.

TMTC3 vs CYSLTR1_S326 — LUAD

Explore this scatter interactively →