TMTC1

Across TCGA cell cohorts, TMTC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,402 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMTC1-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Cellular respiration, and Aerobic respiration. Each is linked with TMTC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both TMTC1-to-partner and partner-to-TMTC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by TMTC1-low versus TMTC1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMTC1→partner) and Y-score (partner→TMTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Energy derivation by oxidation of organic compounds →	+0.067	+1.637	<.001	.001	2	11
BLOOD_Lymphoma	Cellular respiration →	+0.083	+0.890	<.001	.001	3	10
SKIN	Aerobic respiration →	+0.088	+1.838	<.001	<.001	3	9
OVARY	Purine nucleoside triphosphate metabolic process →	+0.070	+1.905	<.001	<.001	3	9
OVARY	Respiratory electron transport chain →	+0.109	+2.357	<.001	<.001	3	9
OVARY	ATP metabolic process →	+0.072	+2.579	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,402 associations by consensus.

Energy derivation by oxidation of organic compounds by TMTC1 expression — SKIN

Explore this box plot interactively →