Across TCGA pan-cancer cohorts, TMSB4XP2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TMSB4XP2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TMSB4XP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMSB4XP2 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

THCA, KIRC, and LUSC are the cancer types where TMSB4XP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMSB4XP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	+0.964	<.001	7	view →
KIRC	Male	All	+0.567	<.001	7	view →
LUSC	Male	All	−0.691	<.001	4	view →
HNSC	All	All	+0.232	.031	3	view →
LIHC	Female	All	+0.280	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: TMSB4XP2 RNA expression & survival · all TMSB4XP2 data types