TMSB4XP1

Across TCGA pan-cancer cohorts, TMSB4XP1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of TMSB4XP1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TMSB4XP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMSB4XP1 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

THCA, LUSC, and KIRC are the cancer types where TMSB4XP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMSB4XP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	+1.634	<.001	8	view →
LUSC	Male	All	−1.001	<.001	6	view →
KIRC	Male	All	+0.698	<.001	6	view →
CHOL	All	All	+1.404	<.001	5	view →
HNSC	Female	IV	+0.808	.002	5	view →
COAD	All	All	−0.572	.004	4	view →
LIHC	Female	II,III,IV	+0.535	.001	4	view →
BRCA	Female	All	+0.334	.003	4	view →
KIRP	All	III,IV	+0.651	.015	3	view →
PAAD	All	All	−1.415	.036	2	view →
STAD	Male	All	−0.648	.037	2	view →
PRAD	All	All	−0.312	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

TMSB4XP1–THCA

Open the THCA breakdown →