TMSB15B-AS1

Across TCGA pan-cancer cohorts, TMSB15B-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated TMSB15B-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher TMSB15B-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TMSB15B-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

UVM, KIRP, and LUSC are the cancer types where TMSB15B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.418	0.894	.003	50	view →
KIRP	OS	Quartile	All	0.863	0.969	.006	49	view →
LUSC	DFS	Median	III,IV	0.379	0.709	<.001	45	view →
PAAD	DFS	Median	All	0.627	0.383	.004	42	view →
LUAD	DFS	Median	II,III,IV	0.615	0.306	<.001	30	view →
STAD	DFS	Median	II,III,IV	0.582	0.787	.010	24	view →
THYM	OS	Median	II,III,IV	0.965	0.666	.002	19	view →
MESO	OS	Median	IV	0.368	0.760	.032	13	view →
COAD	DFS	Tertile	All	0.710	0.853	.024	13	view →
LIHC	OS	Tertile	II,III,IV	0.744	0.436	.004	11	view →
BLCA	OS	Median	III,IV	0.682	0.479	.017	9	view →
READ	DFS	Quartile	All	0.889	0.737	.032	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

TMSB15B-AS1–UVM (OS)

Open the UVM breakdown →