TMPRSS9

Across TCGA cell cohorts, TMPRSS9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,802 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMPRSS9-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Positive regulation of striated muscle contraction, and Nuclear export. Each is linked with TMPRSS9 in more than 14 cancer types. Because this analysis shows association rather than direction, both TMPRSS9-to-partner and partner-to-TMPRSS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by TMPRSS9-low versus TMPRSS9-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS9→partner) and Y-score (partner→TMPRSS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Pre-mRNA catabolic process →	+0.201	+0.571	<.001	<.001	3	15
PANCREAS	Positive regulation of striated muscle contraction →	-0.273	-0.384	<.001	<.001	3	12
OESOPHAGUS	Nuclear export →	+0.081	+0.404	<.001	.006	3	12
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.168	+0.313	<.001	.004	3	12
SOFT_TISSUE	Negative regulation of translational initiation →	+0.082	+0.460	<.001	.004	3	12
SOFT_TISSUE	RNA export from nucleus →	+0.106	+0.342	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,802 associations by consensus.

Pre-mRNA catabolic process by TMPRSS9 expression — LARGE_INTESTINE

Explore this box plot interactively →