TMPRSS7

Across TCGA patient cohorts, TMPRSS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,132 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TMPRSS7-associated GO terms across cancer lineages are Receptor metabolic process, Membrane lipid metabolic process, and Lipoprotein biosynthetic process. Each is linked with TMPRSS7 in more than 15 cancer types. Because this analysis shows association rather than direction, both TMPRSS7-to-partner and partner-to-TMPRSS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Receptor metabolic process grouped by TMPRSS7-low versus TMPRSS7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS7→partner) and Y-score (partner→TMPRSS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Receptor metabolic process →	+0.094	+0.275	<.001	<.001	3	16
STAD	Membrane lipid metabolic process →	+0.042	+0.175	<.001	<.001	3	15
STAD	Lipoprotein biosynthetic process →	+0.049	+0.136	<.001	<.001	3	15
ESCA	Pigment granule localization →	+0.049	+0.353	.001	<.001	3	15
ESCA	Establishment of pigment granule localization →	+0.045	+0.225	<.001	<.001	2	16
ESCA	Intraciliary anterograde transport →	+0.055	+0.218	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,132 associations by consensus.

Receptor metabolic process by TMPRSS7 expression — STAD

Explore this box plot interactively →