Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, TMPRSS6 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible TMPRSS6-associated genes across cancer lineages are Cyclin-E2, Ku80, and Annexin-1. Each is linked with TMPRSS6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMPRSS6-to-partner and partner-to-TMPRSS6 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (TMPRSS6→partner) and Y-score (partner→TMPRSS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.