TMPRSS4

Across TCGA patient cohorts, TMPRSS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,462 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMPRSS4-associated proteins across cancer lineages are CTNND1, RDH10, and CEACAM5. Each is linked with TMPRSS4 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMPRSS4-to-partner and partner-to-TMPRSS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMPRSS4 versus CTNND1 in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS4→partner) and Y-score (partner→TMPRSS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CTNND1 →	+0.254	+1.263	<.001	<.001	3	5
LUAD	RDH10 →	+0.644	+1.410	<.001	<.001	3	4
LSCC	CEACAM5 →	+1.195	+1.214	<.001	<.001	3	4
UCEC	CORO2A →	+0.549	+1.017	<.001	<.001	3	4
LUAD	DHRS3 →	+0.559	+1.449	<.001	<.001	3	4
HNSC	EPB41L1 →	+0.908	+1.613	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,462 associations by consensus.

TMPRSS4 vs CTNND1 — LSCC

Explore this scatter interactively →